![]() ![]() It is part of the UNICORN software for use with ÄKTA protein purification systems. Intelligent packing supports all column sizes. Automated methods brings several benefits, for example, minimized hands-on time and excellent reproducibility. It enables creation of automated methods for packing, unpacking, priming, and maintenance. Handling AxiChrom columns is easy using Intelligent packing. A selection of columns from the AxiChrom platform. The swing-out function is an example of how the design enables a significant reduction in handling time, compared to other column series. In larger columns, 300 to 600 mm i.d., the tube swings out allowing hoist-free handling. The smaller columns, 50 to 200 mm i.d., have a stand with a pivot design. All have a thoughtful design for easy handling and maintenance. A range of column sizes is available, from 50 to 600 mm inner diameter (i.d.). It is also a great solution for manufacturing networks in need for a robust and standardized column solution. This attribute, in combination with automated packing and easy maintenance, make the platform an excellent choice for multipurpose facilities. It enables many configuration possibilities that can fit different needs. AxiChrom is a configurable yet standardized platform. They are excellent for use during process development and manufacturing of biopharmaceutical products. AxiChrom columns are: intelligent: reduced operation time through automation, verified methods, and simplified workflows intuitive: increased uptime through simple design with reduced risk for operator errors predictable: quick and easy technology-transfer through scalable and robust platform design Column description General AxiChrom columns are low-pressure, axial compression chromatography columns. Excellent compatibility of chromatography columns, media, and systems enables reliable results and high productivity. This includes traditional BioProcess media, such as the Sepharose family, as well as high-flow media families, like Capto and MabSelect. The entire AxiChrom column line has been designed and verified to give exceptional performance with a broad range of media (resins). Compared to a conventional column, AxiChrom columns purposeful design makes process chromatography easier, safer, and more efficient. It simplifies column handling at all scales, from pilot to large-scale production. In addition, the potential for pre-packed columns to be gamma sterilized provides a compelling value proposition for companies looking to implement multi-column chromatography.1 AxiChrom columns CHROMATOGRAPHY COLUMNS The AxiChrom column platform (Fig ) is a revolutionary concept in column chromatography. Banks of multiple pre-packed columns can be delivered ready to run eliminating the need for multiple self-packed columns. This transfer of operational risk helps adopters of pre-packed columns to maintain leaner operations and focus on the most critical aspects of making and purifying therapeutic proteins.Īs the industry evolves to incorporate continuous processing, pre-packed columns are a perfect fit for multi-column chromatography. This allows a bioprocessing facility to outsource column packing, a non-value added step for making therapeutic proteins, and no longer worry about column packing issues. The ability of pre-packed column suppliers to focus their operations on column packing results in more consistently packed columns over time. Replacing traditional self-packed glass or stainless steel columns, pre-packed columns are packed by experts in state of the art facilities and are delivered ready to use for GMP processing. Operational flexibility for multi-product facilities.Rapid change over (no column packing, unpacking, or cleaning validation).In particular, adopters of pre-packed columns have realized the following benefits: ![]() Use of pre-packed columns in downstream chromatography has increased in response to the needs of multi-product facilities and initiatives focused on reducing change over time. SpectraPor Tube-A-Lyzer Dialysis Device.SpectraPor Micro Float-A-Lyzer® Ready-to-use Dialysis Device.SpectraPor Standard Grade Regenerated Cellulose (RC) Customized Dialysis Membranes.SpectraPor Pre-treated Standard Grade RC Dialysis Tubing and Trial Kits.SpectraPor Biotech Grade Regenerated Cellulose (RC) Dialysis Membrane.SpectraPor Biotech Grade Cellulose Ester (CE) Dialysis Membrane.SpectraPor 1-5 Dry Standard Grade Regenerated Cellulose (RC) Dialysis Tubing & Trial Kits.SpectraPor 1-4 Standard Grade Regenerated Cellulose (RC) Single-Layer Dialysis Membrane.SpectraPor Pre-wetted Standard Grade RC Dialysis Tubing and Trial Kits. ![]() SpectrPor Dialysis Tubing and Membranes Overview
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